Cardiac Troponin T Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-557-024	Proteintech Group Inc 155131AP150UL	150 μL

Description

Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.

Specifications

• Antigen: Cardiac Troponin T
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P45379, P50752, P50753
• Gene ID (Entrez): 21956, 24837, 7139
• Immunogen: Cardiac Troponin T Fusion Protein Ag7716
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: TNNT2

• Concentration: 0.19 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Cardiac Troponin T, CMH2, cTnT, TNNT2, TnTC
• Gene Symbols: TNNT2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody