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Invitrogen™ Cardiotrophin 1 Polyclonal Antibody
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Catalog No. PIPA543748
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100 μL
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PIPA543748 100 μL
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Catalog No. PIPA543748 Supplier Invitrogen™ Supplier No. PA543748
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Description

Rabbit Polyclonal Antibody

Peptide sequence: MSRREGSLED PQTDSSVSLL PHLEAKIRQT HSLAHLLTKY AEQLLQEYVQ Sequence homology: Cow: 93%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 92%; Rat: 86%.

Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cardiotrophin 1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene CTF1
Gene Accession No. Q16619
Gene Alias cardiophin 1; Cardiotrophin; cardiotrophin 1; Cardiotrophin1; cardiotrophin-1; CT 1; CT1; CT-1; CT-1CT1; CTF 1; Ctf1; IL-6 cytokine family
Gene Symbols CTF1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human CTF1 (aa 1-50).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1489
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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