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Invitrogen™ Cardiotrophin 1 Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA547618
Description
In direct ELISAs and Western blots, approximately 40% cross-reactivity with recombinant human CT-1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.
Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development.
Specifications
Cardiotrophin 1 | |
Polyclonal | |
Unconjugated | |
CTF1 | |
cardiophin 1; Cardiotrophin; cardiotrophin 1; Cardiotrophin1; cardiotrophin-1; CT 1; CT1; CT-1; CT-1CT1; CTF 1; Ctf1; IL-6 cytokine family | |
Goat | |
Antigen affinity chromatography | |
RUO | |
13019 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Neutralization, Western Blot | |
0.2 mg/mL | |
PBS with 5% trehalose and No Preservative | |
Q60753 | |
CTF1 | |
E. coli-derived recombinant mouse Cardiotrophin-1/CT-1 Ser2-Ala203. | |
100 μg | |
Primary | |
Mouse | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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