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Cardiotrophin 1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984800
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50-198-4800 100 μL
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Catalog No. 50-198-4800 Supplier Bioss Supplier No. BS2534R
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Description

Rabbit Polyclonal Antibody

Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development.

Specifications

Antigen Cardiotrophin 1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CTF1
Gene Accession No. Q16619
Gene Alias BOS_22817; cardiophin 1; Cardiotrophin; cardiotrophin 1; Cardiotrophin1; Cardiotrophin-1; CT 1; CT1; CT-1; CT-1CT1; CTF 1; Ctf1
Gene Symbols CTF1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CTF1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1489
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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