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Tocris Bioscience™ Cariporide
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Catalog No. 535810
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Catalog No. Quantity
53-581-0 10 mg
53-585-0 50 mg
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Catalog No. 53-581-0 Supplier Tocris Bioscience™ Supplier No. 5358/10
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Description

Selective NHE1 inhibitor; cardioprotective and antitumor

Cariporide is a selective Na+/H+ exchanger isoform 1 (NHE1) inhibitor (IC50 values are 0.05, 3 and 1000 μM for NHE1, NHE3 and NHE2 respectively). Attenuates ischemia-induced cardiomyocyte apoptosis in vitro. Reduces cardiac arrhythmia in vivo. Also promotes apoptosis in cancer cells overexpressing NHE1. Orally active.

Specifications

Quantity 10 mg
Product Type Cariporide
Purity >99%
Molecular Weight (g/mol) 283.35
Inhibitors Cariporide

For Research Use Only

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