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Invitrogen™ CARKL Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA555063
Description
Immunogen sequence: FLKSYDAAGT IHDYVVAMLC GLPRPLMSDQ NAASWGYFNT QSQSWNVETL RSSGFPVHLL PDIAEPGSVA GRTSHMWFEI PKGTQV Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 85%.
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.
Specifications
CARKL | |
Polyclonal | |
Unconjugated | |
SHPK | |
4930431K22Rik; AI194947; AW260459; Carbohydrate kinase-like protein; CARKL; Sedoheptulokinase; SHK; Shpk | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
23729 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.05 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q9UHJ6 | |
SHPK | |
Recombinant protein corresponding to Human CARKL. Recombinant protein control fragment (Product #RP-93552). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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