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Invitrogen™ CARS Monoclonal Antibody (CL2304)
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Catalog No. PIMA524635
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100 μL
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PIMA524635 100 μL
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Catalog No. PIMA524635 Supplier Invitrogen™ Supplier No. MA524635
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Mouse Monoclonal Antibody

Immunogen sequence: SQCNLYMAAR KAVRKRPNQA LLENIALYLT HMLKIFGAVE EDSSLGFPVG GPGTSLSLEA TVMPYLQVLS EFREGVRKIA REQKVPEILQ LSDALRDNIL PELGVRFEDH EGLPTVVKLV DRNTLLKERE EKRRVE Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%. Binds to an epitope located within the peptide sequence EDSSLGFPVG as determined by overlapping synthetic peptides.

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CARS
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL2304
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CARS1
Gene Accession No. P49589
Gene Alias CA3; CARS; cars protein; CARS1; CYSRS; cysteine translase; cysteine tRNA ligase 1, cytoplasmic; cysteine--tRNA ligase, cytoplasmic; Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 1; cysteinyl-tRNA synthetase, cytoplasmic; LOW QUALITY PROTEIN: cysteine--tRNA ligase, cytoplasmic; MGC:11246; sb:cb71
Gene Symbols CARS, CARS1
Host Species Mouse
Immunogen Recombinant protein fragment of Human CARS (Product #RP-101867)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 833
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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