Invitrogen™ CARS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578914

Catalog No. PIPA578914

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela cell, human COLO-320 cell, human A549 cell, human PANC-1 cell, human 22RV1 cell. IHC: human placenta tissue. ICC/IF: U20S cell. Flow: A431 cell.

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: CARS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CARS1
• Gene Alias: CA3; CARS; cars protein; CARS1; CYSRS; cysteine translase; cysteine tRNA ligase 1, cytoplasmic; cysteine--tRNA ligase, cytoplasmic; Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 1; cysteinyl-tRNA synthetase, cytoplasmic; LOW QUALITY PROTEIN: cysteine--tRNA ligase, cytoplasmic; MGC:11246; sb:cb71
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 833
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P49589
• Gene Symbols: CARS, CARS1
• Immunogen: E. coli-derived human CARS recombinant protein (Position: D510-Q748).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG