Invitrogen™ CARS Recombinant Rabbit Monoclonal Antibody (7V0X1)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542593

Catalog No. PIMA542593

Description

Positive test controls include: HeLa, A-549, MCF7, U-87MG, Rat pancreas. The target is usually found in the following locations: Cytoplasm. Immunogen sequence: EREEKRRVEE EKRKKKEEAA RRKQEQEAAK LAKMKIPPSE MFLSETDKYS KFDENGLPTH DMEGKELSKG QAKKLKKLFE AQEKLYKEYL QMAQNGSFQ.

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: CARS
• Classification: Recombinant Monoclonal
• Concentration: 0.4 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P49589
• Gene Symbols: CARS, CARS1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 650-748 of human CARS (P49589).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 7V0X1
• Conjugate: Unconjugated
• Gene: CARS1
• Gene Alias: CA3; CARS; cars protein; CARS1; CYSRS; cysteine translase; cysteine tRNA ligase 1, cytoplasmic; cysteine--tRNA ligase, cytoplasmic; Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 1; cysteinyl-tRNA synthetase, cytoplasmic; LOW QUALITY PROTEIN: cysteine--tRNA ligase, cytoplasmic; MGC:11246; sb:cb71
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 293638, 833
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid