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Invitrogen™ CAS Recombinant Rabbit Monoclonal Antibody (JU34-33)
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Catalog No. PIMA534638
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100 μL
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PIMA534638 100 μL
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Catalog No. PIMA534638 Supplier Invitrogen™ Supplier No. MA534638
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Mouse testis tissue, SiHa, SK-BR-3, PC-3M, LOVO, SH-SY5Y, human colon cancer tissue, LOVO.

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CAS
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JU34-33
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene CSE1L
Gene Accession No. P55060
Gene Alias 2610100P18Rik; AA407533; Capts; CAS; Cellular apoptosis susceptibility protein; chromosome segregation 1 like; chromosome segregation 1-like (S. cerevisiae); chromosome segregation 1-like protein; CSE1; CSE1 chromosome segregation 1 like; CSE1 chromosome segregation 1-like; CSE1 chromosome segregation 1-like (yeast); CSE1L; Exp2; exportin-2; Importin-alpha re-exporter; MGC117283; MGC130036; MGC130037; XPO2
Gene Symbols CSE1L
Host Species Rabbit
Immunogen Recombinant protein within Human Cellular Apoptosis Susceptibility aa 860-971.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1434
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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