Cas9 Monoclonal Antibody (OTI2B9), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-3877	100 μL

Catalog No. 50-168-3877 Supplier OriGene Supplier No. TA811175

Description

Mouse Monoclonal Antibody

CRISPR systems are adaptable immune mechanisms which are present in many bacteria to protect themselves from foreign nucleic acids, such as viruses, transposable elements, or plasmids. Recently, the CRISPR/Cas9 system from S. pyogenes has been adapted for inducing sequence-specific double stranded breaks and targeted genome editing. This system is unique and flexible due to its dependence on RNA as the element that targets the nuclease to a desired DNA sequence. It can be used to induce indel mutations, specific sequence replacements/insertions, and large deletions or genomic rearrangements at any desired location in the genome. In addition, Cas9 can also be used to mediate upregulation of specific endogenous genes or to alter histone modifications or DNA methylation.

Specifications

• Antigen: CAS9
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI2B9
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Alias: Cas9Cas9; Cas9
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-1166 of human CAS9 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Bacteria
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1