CAS9 Mouse anti-Bacteria, Clone: OTI2B9, lyophilized, TrueMAB™

Catalog No.	Quantity
50-167-0494	100 μg

Catalog No. 50-167-0494 Supplier OriGene Supplier No. CF811175

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

CRISPR systems are adaptable immune mechanisms which are present in many bacteria to protect themselves from foreign nucleic acids, such as viruses, transposable elements, or plasmids. Recently, the CRISPR/Cas9 system from S. pyogenes has been adapted for inducing sequence-specific double stranded breaks and targeted genome editing. This system is unique and flexible due to its dependence on RNA as the element that targets the nuclease to a desired DNA sequence. It can be used to induce indel mutations, specific sequence replacements/insertions, and large deletions or genomic rearrangements at any desired location in the genome. In addition, Cas9 can also be used to mediate upregulation of specific endogenous genes or to alter histone modifications or DNA methylation.

Specifications

• Antigen: CAS9
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI2B9
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Alias: Cas9Cas9; Cas9
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-1166 of human CAS9 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Bacteria
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1