CAS9 Mouse anti-Bacteria, Clone: OTI6D9, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811194

Catalog No. 50-167-0510

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

CRISPR systems are adaptable immune mechanisms which are present in many bacteria to protect themselves from foreign nucleic acids, such as viruses, transposable elements, or plasmids. Recently, the CRISPR/Cas9 system from S. pyogenes has been adapted for inducing sequence-specific double stranded breaks and targeted genome editing. This system is unique and flexible due to its dependence on RNA as the element that targets the nuclease to a desired DNA sequence. It can be used to induce indel mutations, specific sequence replacements/insertions, and large deletions or genomic rearrangements at any desired location in the genome. In addition, Cas9 can also be used to mediate upregulation of specific endogenous genes or to alter histone modifications or DNA methylation.

Specifications

• Antigen: CAS9
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene Alias: Cas9Cas9; Cas9
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-1166 of human CAS9 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI6D9
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Target Species: Bacteria
• Product Type: Antibody
• Isotype: IgG2a