Invitrogen™ CASC4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560201

Catalog No. PIPA560201

Description

Immunogen sequence: NTYLVKRLEY ESFQCGQQMK ELRAQHEENI KKLADQFLEE QKQETQKIQS NDGKELDINN QVVPKNIPKV AENVADKNE Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.

The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.

Specifications

• Antigen: CASC4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CASC4
• Gene Alias: cancer susceptibility candidate 4; cancer susceptibility candidate gene 4 protein; Cancer susceptibility candidate gene 4 protein homolog; Casc4; D130060C09Rik; gene associated with HER-2/neu overexpression; H63; Protein CASC4; UNQ2573/PRO6308; VGFG2573
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113201
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6P4E1
• Gene Symbols: CASC4
• Immunogen: Recombinant protein corresponding to Human CASC4. Recombinant protein control fragment (Product #RP-99877).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov