Invitrogen™ CASK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA125080

Catalog No. PIPA125080

Description

Recommended positive controls: Jurkat, MDCK. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CASK is a calcium/calmodulin-dependent serine protein kinase which is a MAGUK (membrane-associated guanylate kinase) protein family member. CASK is a scaffold protein and the encoded protein is located at synapses in the brain. CASK associates with FG syndrome 4, mental retardation, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. CASK functions as a cytoskeletal membrane scaffold that coordinates signal transduction pathways within the cortical cytoskeleton.

Specifications

• Antigen: CASK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cask
• Gene Alias: CAGH39; calcium/calmodulin dependent serine protein kinase; calcium/calmodulin-dependent serin protein kinase; Calcium/calmodulin-dependent serine protein kinase; calcium/calmodulin-dependent serine protein kinase (MAGUK family); calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase; CAMGUK; CASK; CMG; DXPri1; DXRib1; FGS4; G-protein-coupled receptor GPR34; hCASK; LIN2; LIN-2; MGC7449; MICPCH; mLin-2; MRXSNA; OTTHUMP00000023157; OTTHUMP00000023161; OTTHUMP00000023162; Pals3; peripheral plasma membrane protein CASK; Protein lin-2 homolog; RP23-278L4.1; TNRC8; trinucleotide repeat containing 8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 480887, 8573
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA and 15mM sodium azide; pH 7.4
• Gene Accession No.: O14936
• Gene Symbols: Cask
• Immunogen: Synthetic peptide, conjugated to KLH, corresponding to residues K(393) S S P Q I R N P P S D A V Q R A(409) of human CASK.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Canine
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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