CASP7 Mouse anti-Human, Clone:4D10B2, Abnova™

Catalog No.	Quantity
89-333-137	100 μg

Catalog No. 89-333-137 Supplier Abnova Corporation Supplier No. MAB16645

Description

Mouse monoclonal antibody raised against recombinant human CASP7.

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq]

Specifications

• Antigen: CASP7
• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 4D10B2
• Conjugate: Unconjugated
• Description: caspase 7, apoptosis-related cysteine peptidase
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry (1:200-1:1000)
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: CASP7
• Gene Alias: CMH-1, ICE-LAP3, MCH3
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 29-198 of human CASP7 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 840
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1