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Invitrogen™ Caspase 1 Polyclonal Antibody
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Catalog No. PIPA517570
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100 μL
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Catalog No. Quantity
PIPA517570 100 μL
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Catalog No. PIPA517570 Supplier Invitrogen™ Supplier No. PA517570
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Description

Rabbit Polyclonal Antibody

PA5-17570 detects Caspase 1 in WB application with human samples. It is not recommended to aliquot this antibody.

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18. Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 125 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene CASP1
Gene Accession No. P29466
Gene Alias CASP1; CASP-1; CASP1 nirs variant 1; caspase 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Caspase1; caspase-1; Caspase-1 subunit p10; Caspase-1 subunit p20; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL1BC; IL-1BC; IL1BCE; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin 1beta converting enzyme; interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45
Gene Symbols CASP1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues within the p20 subunit of human caspase-1.
Purification Method Antigen affinity chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 834
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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