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Invitrogen™ Caspase 14 Recombinant Rabbit Monoclonal Antibody (006), FITC
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Catalog No. PIMA540982
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100 Tests
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PIMA540982 100 Tests
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Catalog No. PIMA540982 Supplier Invitrogen™ Supplier No. MA540982
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Description

Rabbit Recombinant Monoclonal Antibody

May be stored for twelve months without detectable loss of activity. Protect from prolonged exposure to light and do not freeze. Sodium azide is toxic to cells and should be disposed of properly so flush with large volumes of water during disposal.

Caspase 14 encodes a member of the cysteine-aspartic acid protease (caspase) family, which plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. Diseases associated with CASP14 include Ichthyosis, Congenital, Autosomal Recessive 12 and Autosomal Recessive Congenital Ichthyosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 14
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone 006
Concentration 0.1 mg/mL
Conjugate FITC
Formulation PBS with 0.5% BSA and 0.09% sodium azide
Gene Casp14
Gene Accession No. P31944
Gene Alias apoptosis-related cysteine protease; CASP14; CASP-14; caspase 14; caspase 14, apoptosis-related cysteine peptidase; caspase 14, apoptosis-related cysteine protease; Caspase14; caspase-14; Caspase-14 subunit p10, mature form; Caspase-14 subunit p17, mature form; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8, intermediate form; caspase-14; LOW QUALITY PROTEIN: caspase-14; MICE; Mini-ICE
Gene Symbols Casp14
Host Species Rabbit
Immunogen Recombinant Human Caspase-14/CASP14 protein.
Purification Method Protein A
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23581
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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