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Invitrogen™ Caspase 2 Monoclonal Antibody (18E809.3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA191729

Catalog No. PIMA191729


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Description

Description

This antibody is expected to cross-react with mouse and rat Caspase-2 based on sequence homology.

Caspase 2 gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Caspase 2
Monoclonal
Conc. Not Determined
Ascites, PBS with 0.2% gelatin and 0.05% sodium azide
P42575
CASP2
A peptide corresponding to amino acids 400-450 of human Caspase-2 was used as immunogen.
200 μL
Primary
Human
Antibody
IgM
Western Blot
18E809
Unconjugated
CASP2
CASP2; CASP-2; caspase 2; caspase 2 apoptosis-related cysteine peptidase; caspase-2; Caspase-2 subunit p12; Caspase-2 subunit p13; Caspase-2 subunit p18; ICH1; ICH-1; ICH-1 protease; ICH-1L; ICH-1L/1S; NEDD2; NEDD-2; Neural precursor cell expressed developmentally down-regulated protein 2; PPP1R57; Protease ICH-1; protein phosphatase 1, regulatory subunit 57
Mouse
IgM
RUO
835
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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