Invitrogen™ Caspase 2 Monoclonal Antibody (18E809.3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA191729

Catalog No. PIMA191729

Description

This antibody is expected to cross-react with mouse and rat Caspase-2 based on sequence homology.

Caspase 2 gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

Specifications

• Antigen: Caspase 2
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites, PBS with 0.2% gelatin and 0.05% sodium azide
• Gene Accession No.: P42575
• Gene Symbols: CASP2
• Immunogen: A peptide corresponding to amino acids 400-450 of human Caspase-2 was used as immunogen.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM

• Applications: Western Blot
• Clone: 18E809
• Conjugate: Unconjugated
• Gene: CASP2
• Gene Alias: CASP2; CASP-2; caspase 2; caspase 2 apoptosis-related cysteine peptidase; caspase-2; Caspase-2 subunit p12; Caspase-2 subunit p13; Caspase-2 subunit p18; ICH1; ICH-1; ICH-1 protease; ICH-1L; ICH-1L/1S; NEDD2; NEDD-2; Neural precursor cell expressed developmentally down-regulated protein 2; PPP1R57; Protease ICH-1; protein phosphatase 1, regulatory subunit 57
• Host Species: Mouse
• Purification Method: IgM
• Regulatory Status: RUO
• Gene ID (Entrez): 835
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid