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Invitrogen™ Caspase 2 Polyclonal Antibody
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Catalog No. PIPA130417
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PIPA130417 1 mL
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Catalog No. PIPA130417 Supplier Invitrogen™ Supplier No. PA130417
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HL-60 and Jurkat.

Caspase 2 gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 2
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin and 0.1% sodium azide
Gene CASP2
Gene Accession No. P29594, P42575, P55215
Gene Alias CASP2; CASP-2; caspase 2; caspase 2 apoptosis-related cysteine peptidase; caspase-2; Caspase-2 subunit p12; Caspase-2 subunit p13; Caspase-2 subunit p18; ICH1; ICH-1; ICH-1 protease; ICH-1L; ICH-1L/1S; NEDD2; NEDD-2; Neural precursor cell expressed developmentally down-regulated protein 2; PPP1R57; Protease ICH-1; protein phosphatase 1, regulatory subunit 57
Gene Symbols CASP2
Host Species Rabbit
Immunogen Peptide mapping to the carboxy terminal of human caspase-2L.
Purification Method Affinity chromatography
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12366, 64314, 835
Target Species Human, Mouse, Rat
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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