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Invitrogen™ Caspase 2 Precursor Recombinant Rabbit Monoclonal Antibody (2Z10F1)
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Catalog No. PIMA535599
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100 μL
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PIMA535599 100 μL
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Catalog No. PIMA535599 Supplier Invitrogen™ Supplier No. MA535599
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: GKNHTQSPGC EESDAGKEEL MKMRLPTRSD MICGYACLKG NAAMRNTKRG SWYIEALTQV FSERACDMHV ADMLVKVNAL IKEREGYAPG TEFHRCKEMS EYCSTLCQQL YLFPGYPPT.

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 2 Precursor
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 2Z10F1
Concentration 2.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CASP2
Gene Accession No. P42575
Gene Alias CASP2; CASP-2; caspase 2; caspase 2 apoptosis-related cysteine peptidase; caspase-2; Caspase-2 subunit p12; Caspase-2 subunit p13; Caspase-2 subunit p18; Ich1; ICH-1; ICH-1 protease; ICH-1L; ICH-1L/1S; Nedd2; NEDD-2; Neural precursor cell expressed developmentally down-regulated protein 2; PPP1R57; Protease ICH-1; protein phosphatase 1, regulatory subunit 57
Gene Symbols CASP2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 334-452 of human Caspase-2 (P29594).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 835
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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