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Thermo Scientific Chemicals Caspase-3 Inhibitor III

Catalog No. AAJ64442MCR
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Catalog No. AAJ64442MCR Supplier Thermo Scientific Chemicals Supplier No. J64442MCR
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Description

A potent, cell-permeable, and irreversible inhibitor of caspase-3; also inhibits caspases -6, -7, -8, and -10. Commonly used at concentrations up to 100 -M to examine the role of caspase-3-dependent apoptosis

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 285570-60-7
Molecular Formula C21H31ClN4O11
Synonym Ac-DEVD-CMK; N-Acetyl-Asp-Glu-Val-Asp chloromethyl ketone

Specifications

Quantity 1 mg
Description Off-white to brown
Content And Storage -30°C to -10°C
For Use With (Application) A potent, cell-permeable, and irreversible inhibitor of caspase-3; also inhibits caspases -6, -7, -8, and -10. Commonly used at concentrations up to 100 →M to examine the role of caspase-3-dependent apoptosis
Formula Weight 550.94
Solubility Soluble in DMSO
Form Powder
InChI Key ATNOUPFYBMVFLD-UHFFFAOYNA-N
SMILES CC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(C)=O)C(=O)NC(CC(O)=O)C(=O)CCl
IUPAC Name 3-{2-[4-carboxy-2-(3-carboxy-2-acetamidopropanamido)butanamido]-3-methylbutanamido}-5-chloro-4-oxopentanoic acid
Molecular Weight (g/mol) 550.95
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Safety and Handling

Recommended Storage Store at -20°C
SDS

RUO – Research Use Only

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