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Invitrogen™ Caspase 4/5 p20 (Cleaved Asp270, Asp311) Polyclonal Antibody
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Catalog No. PIPA539873
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100 μg
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PIPA539873 100 μg
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Catalog No. PIPA539873 Supplier Invitrogen™ Supplier No. PA539873
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Rabbit Polyclonal Antibody

Caspase 4/5 p20 (Cleaved Asp270, Asp311) Polyclonal Antibody for Western Blot

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 4/5 p20 (Cleaved Asp270, Asp311)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco's PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CASP4
Gene Accession No. P49662, P51878
Gene Alias apoptotic cysteine protease Mih1/TX; CASP4; CASP-4; CASP5; CASP-5; caspase 4; caspase 4, apoptosis-related cysteine peptidase; caspase 4, apoptosis-related cysteine protease; caspase 5; caspase 5, apoptosis-related cysteine peptidase; caspase 5, apoptosis-related cysteine protease; caspase-4; Caspase-4 subunit 1; Caspase-4 subunit 2; Caspase-5; Caspase-5 subunit p10; Caspase-5 subunit p20; ICE and Ced-3 homolog 2; ICE(rel)II; ICE(rel)-II; ICE(rel)III; ICE(rel)-III; ICEREL-II; ICEREL-III; ICH2; ICH-2; ICH3; ICH-3; Mih1; Mih1/TX; protease ICH-2; protease ICH-3; protease protease ICE(rel)III; protease protease TY; Protease TX; protease TY; TX; TY protease
Gene Symbols CASP4, CASP5
Host Species Rabbit
Immunogen A synthetic peptide derived from human Caspase 4/5.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 837, 838
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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