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Invitrogen™ Caspase 4 Monoclonal Antibody (OTI4A2)
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Catalog No. PIMA526748
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100 μL
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PIMA526748 100 μL
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Catalog No. PIMA526748 Supplier Invitrogen™ Supplier No. MA526748
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Description

Mouse Monoclonal Antibody

Caspase 4 Monoclonal Antibody for Western Blot, ICC/IF

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 4
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone OTI4A2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CASP4
Gene Accession No. P49662
Gene Alias apoptotic cysteine protease Mih1/TX; Casp11; CASP-11; CASP4; CASP-4; caspase 11; caspase 4; caspase 4, apoptosis-related cysteine peptidase; caspase 4, apoptosis-related cysteine protease; Caspase-11; Caspase-4; Caspase-4 subunit 1; Caspase-4 subunit 2; Caspase-4 subunit p10; Caspase-4 subunit p20; Caspl; ICE and Ced-3 homolog 2; ICE(rel)II; ICE(rel)-II; ICEREL-II; ICH2; ICH-2; Ich3; ich-3; Mih1; Mih1/TX; protease ICH-2; Protease ICH-3; Protease TX; TX
Gene Symbols CASP4
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 81-270 of CASP4 produced in E.coli.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 837
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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