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Invitrogen™ Caspase 4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5118880
Description
Antibody detects endogenous levels of total Caspase 11.
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Specifications
Caspase 4 | |
Polyclonal | |
Unconjugated | |
CASP4 | |
apoptotic cysteine protease Mih1/TX; Casp11; CASP-11; CASP4; CASP-4; caspase 11; caspase 4; caspase 4, apoptosis-related cysteine peptidase; caspase 4, apoptosis-related cysteine protease; Caspase-11; Caspase-4; Caspase-4 subunit 1; Caspase-4 subunit 2; Caspase-4 subunit p10; Caspase-4 subunit p20; Caspl; ICE and Ced-3 homolog 2; ICE(rel)II; ICE(rel)-II; ICEREL-II; ICH2; ICH-2; Ich3; ich-3; Mih1; Mih1/TX; protease ICH-2; Protease ICH-3; Protease TX; TX | |
Rabbit | |
Affinity Chromatography | |
RUO | |
114555, 12363, 837 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P49662, P70343 | |
CASP4 | |
A synthesized peptide derived from human Caspase 11. | |
100 μL | |
Primary | |
Human, Mouse, Rat, Monkey | |
Antibody | |
IgG |
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