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Invitrogen™ Caspase 5 Polyclonal Antibody
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Catalog No. PIPA5102876
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100 μL
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PIPA5102876 100 μL
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Catalog No. PIPA5102876 Supplier Invitrogen™ Supplier No. PA5102876
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Caspase 5.

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1-b and IL-18. Caspase-5 can interact with caspase-1; both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1-b. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 5
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CASP5
Gene Accession No. P51878
Gene Alias CASP5; CASP-5; caspase 5; caspase 5, apoptosis-related cysteine peptidase; caspase 5, apoptosis-related cysteine protease; caspase-5; Caspase-5 subunit p10; Caspase-5 subunit p20; ICE(rel)III; ICE(rel)-III; ICEREL-III; ICH3; ICH-3; Protease ICH-3; protease TY; TY protease
Gene Symbols CASP5
Host Species Rabbit
Immunogen A synthesized peptide derived from human CASP5(Accession P51878), corresponding to amino acid residues S118-R168.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 838
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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