Invitrogen™ Caspase 6 Recombinant Rabbit Monoclonal Antibody (2W4G2)

Catalog No.	Quantity
PIMA535299	100 μL

Catalog No. PIMA535299 Supplier Invitrogen™ Supplier No. MA535299

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: IHEVSTVSHA DADCFVCVFL SHGEGNHIYA YDAKIEIQTL TGLFKGDKCH SLVGKPKIFI IQACRGNQHD VPVIPLDVVD NQTEKLDTNI TEVDAASVYT L.

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

Specifications

• Antigen: Caspase 6
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 2W4G2
• Concentration: 0.66 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: Casp6
• Gene Accession No.: O08738, P55212
• Gene Alias: apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
• Gene Symbols: Casp6
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Caspase-6 (P55212).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12368, 839
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG