Invitrogen™ Caspase 6 Monoclonal Antibody (C1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA541562

Catalog No. PIMA541562

Description

Caspase 6 Monoclonal Antibody for Western Blot, IHC (P)

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

Specifications

• Antigen: Caspase 6
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q3T0P5
• Gene Symbols: Casp6
• Immunogen: Recombinant protein Caspase 6.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Bovine
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Clone: C1
• Conjugate: Unconjugated
• Gene: Casp6
• Gene Alias: apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 538409
• Content And Storage: -20°C
• Form: Liquid