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Invitrogen™ Caspase 6 Monoclonal Antibody (C6), Invitrogen™
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Catalog No. FEMA551055
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FEMA551055 200 μL
FEMA551056 20 μL
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Catalog No. FEMA551055 Supplier Invitrogen™ Supplier No. MA551055
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Mouse Monoclonal Antibody

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
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Specifications

Antigen Caspase 6
Applications Western Blot
Classification Monoclonal
Clone C6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene Casp6
Gene Accession No. Q3T0P5
Gene Alias apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
Gene Symbols Casp6
Host Species Mouse
Immunogen Recombinant Bovine CASP6 protein, Ala194-Asn293 (Accession #Q3T0P5).
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 538409
Target Species Bovine
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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