Invitrogen™ Caspase 6 p18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578922

Catalog No. PIPA578922

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Jurkat whole cell. IHC: human colorectal adenocarcinoma tissue, human pancreatic cancer tissue. Flow: SiHa cell.

Caspase 6 is an enzyme that in humans is encoded by the caspase 6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Using radiation hybrid mapping, the Caspase 6 gene is localized to human chromosome 4q25-q26. Caspase 6 functions as a downstream enzyme in the caspase activation cascade. And Caspase 6 can cleave lamin A to its signature apoptotic fragment.

Specifications

• Antigen: Caspase 6 p18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CASP6
• Gene Alias: apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; MCH2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 839
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: P55212
• Gene Symbols: CASP6
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-6 (P18) (24-44aa AFYKREMFDPAEKYKMDHRRR).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov