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Invitrogen™ Caspase 6 Polyclonal Antibody
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Catalog No. PIPA5143079
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100 μg
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PIPA5143079 100 μg
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Catalog No. PIPA5143079 Supplier Invitrogen™ Supplier No. PA5143079
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize both reported isoforms (NP_001217.2; NP_116787.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 6
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Casp6
Gene Accession No. P55212
Gene Alias apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
Gene Symbols Casp6
Host Species Goat
Immunogen Peptide with sequence C-QTEKLDTNITEVD (aa 181-193).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 839
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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