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Caspase-6 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980097
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50-198-0097 100 μL
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Catalog No. 50-198-0097 Supplier Bioss Supplier No. BS0151R
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Description

Rabbit Polyclonal Antibody

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

Specifications

Antigen Caspase-6
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Casp6
Gene Accession No. P55212
Gene Alias Apoptotic protease Mch-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; Caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
Gene Symbols Casp6
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Caspase-6.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 839
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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