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Invitrogen™ Caspase 7 p11 Polyclonal Antibody
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Catalog No. PIPA532146
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100 μL
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Catalog No. Quantity
PIPA532146 100 μL
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Catalog No. PIPA532146 Supplier Invitrogen™ Supplier No. PA532146
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, Jurakt, Jurakt (10 μM etoposide treatment for 24 hr). Predicted reactivity: Mouse (91%), Rat (91%), Zebrafish (83%), Xenopus laevis (82%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 7 p11
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.93 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene CASP7
Gene Accession No. P55210
Gene Alias AI314680; Apoptotic protease Mch-3; Casp7; CASP-7; caspase 7; caspase 7, apoptosis-related cysteine peptidase; caspase 7, apoptosis-related cysteine protease; caspase-7; Caspase-7 subunit p11; Caspase-7 subunit p20; CMH-1; cysteine protease LICE2; ICE-IAP3; ICE-LAP3; ICE-like apoptotic protease 3; LICE2; mCASP-7; MCH3
Gene Symbols CASP7
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human Caspase 7. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 840
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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