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Caspase 9/p35/p10 Mouse anti-Human, Mouse, Clone: 1B7G2, Proteintech
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Catalog No. 501736603 Shop All Proteintech Group Inc Products
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50-173-6603 150 μL
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Catalog No. 50-173-6603 Supplier Proteintech Group Inc Supplier No. 661691IG150UL
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Mouse Monoclonal Antibody

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

Specifications

Antigen Caspase 9/p35/p10
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 1B7G2
Concentration 1.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CASP9
Gene Accession No. P55211, Q8C3Q9
Gene Alias APAF 3, APAF3, Apoptotic protease Mch 6, CASP 9, CASP9, Caspase 9, Caspase 9/p35/p10, CASPASE 9c, Caspase9, Caspase-9, ICE LAP6, ICE like apoptotic protease 6, MCH6
Gene Symbols CASP9
Host Species Mouse
Immunogen Caspase 9/p35/p10 Fusion Protein Ag20813
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12371, 842
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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