CASPR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-6148	150 μL

Catalog No. 50-173-6148 Supplier Proteintech Group Inc Supplier No. 554171AP150UL

Description

Rabbit Polyclonal Antibody

This antibody is specific to CNTNAP1.

CNTNAP1 was initially identified as a 190-kDa protein associated with the contactin-PTPRZ1 complex. The 1, 384-amino acid protein, also designated p190 or CASPR for ′contactin-associated protein, ′ includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. The gene product was initially identified as a 190-kDa protein associated with the contactin-PTPRZ1 complex. The 1, 381-amino acid protein, also designated p190 or CASPR for ′contactin-associated protein, ′ includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predomitly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Specifications

• Antigen: CASPR
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.4 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: CNTNAP1
• Gene Accession No.: O54991, P78357, P97846
• Gene Alias: CASPR, Caspr1, CNTNAP, CNTNAP1, contactin associated protein 1, Neurexin 4, Neurexin IV, NRXN4, P190
• Gene Symbols: Cntnap1
• Host Species: Rabbit
• Immunogen: Peptide
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 53321, 84008, 8506
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG