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Invitrogen™ Caspr2 Polyclonal Antibody
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Catalog No. PIPA517166
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100 μL
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PIPA517166 100 μL
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Catalog No. PIPA517166 Supplier Invitrogen™ Supplier No. PA517166
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.
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Specifications

Antigen Caspr2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene CNTNAP2
Gene Accession No. Q9CPW0, Q9UHC6
Gene Alias 5430425M22Rik; AUTS15; CASPR2; CDFE; Cell recognition molecule Caspr2; Cntnap2; contactin associated protein-like 2; contactin-associated protein-like 2; DKFZp781D1846; homolog of Drosophila neurexin IV; KIAA0868; mKIAA0868; NRXN4; PTHSL1
Gene Symbols CNTNAP2
Host Species Rabbit
Immunogen Synthetic peptide sourrounding Glu1320 of human Caspr2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26047, 500105, 66797
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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