CAST Monoclonal Antibody (OTI1E7), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA504351

Catalog No. 50-167-5067

Description

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: CAST
• Classification: Monoclonal
• Concentration: 0.62 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P20810
• Gene Symbols: CAST
• Immunogen: Full length human recombit protein of human CAST produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1E7
• Conjugate: Unconjugated
• Gene: CAST
• Gene Alias: BS-17, PLACK
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 831
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid