Invitrogen™ CAT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109589

Catalog No. PIPA5109589

Description

Immunogen sequence: KLRFNITPEI KSDIEKAKQN LSIMIQDLDI TVMVFHHFGK DFPKSEKLSP DAFIQMALQL AYYRIYGQAC ATYESASLRM FHLGRTDTIR SASMDSLTFV KAMDDSSVTE HQKVELLRKA VQAHRGYTDR AIRGEAFDRH LLGLKLQAIE DLVSMPDIFM DTSYAIAMHF HLSTSQVPAK TDCVMFFGPV VPDGYGVCYN PMEAHINFSL SAYNSCAETN AARLAHYLEK ALLDMRALLQ SHPRAKL.

Carnitine acetyltransferase (CRAT) is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Different subcellular localizations of the CRAT mRNAs are thought to result from alternative splicing of the CRAT gene suggested by the divergent sequences in the 5' region of peroxisomal and mitochondrial CRAT cDNAs and the location of an intron where the sequences diverge. The alternatively splicing of this gene results in three distinct isoforms, one of which contains an N-terminial mitochondrial transit peptide, and has been shown to be located in mitochondria.

Specifications

• Antigen: CAT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CRAT
• Gene Alias: amino acid transporter, cationic 1; ATRC1; AW107812; CARAT; Carnitine acetylase; carnitine acetyltransferase; Carnitine O-acetyltransferase; CAT; CAT1; CAT-1; Crat; Ecotropic retroviral leukemia receptor homolog; ecotropic retroviral receptor; ecotropic retrovirus receptor homolog; ERR; HCAT1; High affinity cationic amino acid transporter 1; REC1L; SLC7A1; solute carrier family 7 (cationic amino acid transporter, y+ system), member 1; solute carrier family 7 member 1; System Y+ basic amino acid transporter
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12908, 1384, 311849
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.69 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P43155, P47934, Q704S8
• Gene Symbols: CRAT
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 380-626 of human CRAT (NP_0007463).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG