Invitrogen™ Catalase Polyclonal Antibody

Catalog No.	Quantity
PIPA595349	100 μg

Catalog No. PIPA595349 Supplier Invitrogen™ Supplier No. PA595349

Description

Rabbit Polyclonal Antibody

Human Catalase shares 85.3% and 82.6% amino acid (aa) sequence identity with mouse and rat Catalase, respectively. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human A549 whole cell, human HL-60 whole cell, human THP-1 whole cell, human U937 whole cell, human HepG2 whole cell, human K562 whole cell, human HCCT tissue, human HCCP tissue, rat liver tissue, rat kidney tissue, rat lung tissue, rat RH35 whole cell, mouse liver tissue, mouse kidney tissue, mouse lung tissue. IHC: mouse liver tissue, rat liver tissue, human liver cancer tissue. ICC/IF: A431 cell. Flow: SiHa cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen. Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size. Catalase has been implicated as an important factor in inflammation, mutagenesis, prevention of apoptosis, and stimulation of a wide spectrum of tumors. Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara's disease.

Specifications

• Antigen: Catalase
• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene: Cat
• Gene Accession No.: P04040, P04762, P24270
• Gene Alias: 2210418N07; Cas1; Cas-1; CAT; Cat01; catalase; catalase 1; Catl; CS1; Cs-1; CTA1; HGNC:1516; hypothetical protein LOC531682; MGC138422; MGC138424
• Gene Symbols: Cat
• Host Species: Rabbit
• Immunogen: E.coli-derived human Catalase recombinant protein (Position: E344-L527).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12359, 24248, 847
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG