Catalase Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Supplier:  Rockland Immunochemicals 200401051

Catalog No. 50-199-0786

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Anti-Catalase Antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum as well as purified and partially purified Catalase [Bovine liver]. Cross reactivity against Catalase from other tissues and species may occur but have not been specifically determined.

Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen. Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size. Catalase has been implicated as an important factor in inflammation, mutagenesis, prevention of apoptosis, and stimulation of a wide spectrum of tumors. Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara's disease.

Specifications

• Antigen: Catalase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cat
• Gene Alias: 2210418N07; BOS_15095; Cas1; Cas-1; CAT; Cat01; Catalase; catalase 1; Catl; CS1; Cs-1; CTA1; HGNC:1516; MGC138422; MGC138424
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Bovine, Human, Mouse, Ovine, Rat
• Product Type: Antibody

• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: P00432, P04040, P04762, P24270
• Gene Symbols: Cat
• Immunogen: Anti-Catalase Antibody was produced by repeated immunizations with bovine liver catalase protein.
• Regulatory Status: RUO
• Gene ID (Entrez): 100307035, 12359, 24248, 531682, 847
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid