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Epredia™ Lab Vision™ Catenin, β Ab-2, Rabbit Polyclonal Antibody

Catalog No. RB1491R1 Shop All Epredia Products
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RB1491R1 1 mL
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Catalog No. RB1491R1 Supplier Epredia™ Supplier No. RB1491R1

Description

Obtain accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

The catenins (α, Β and γ) are ubiquitously expressed cytoplasmic proteins associated with E-cadherin at cellular junctions. Β-catenin also binds to N-cadherin and co-immunoprecipitates with APC. Cadherin/catenin complexes are linked to the cytoskeleton via a direct association between α-actinin and α-catenin. Increased tyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellular adhesion.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Chicken and Xenopus. Others not tested.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminus of the β-catenin protein

Molecular Weight: 92 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Cytoplasmic and cell membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Catenin, beta Ab-2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Rabbit
Immunogen A synthetic peptide from the C-terminus of the Beta-catenin protein
Quantity 1 mL
Regulatory Status RUO
Research Discipline Cell Adhesion
Primary or Secondary Primary
Target Species Chicken, Human, Mouse, Rat
Form Prediluted
Isotype IgG
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