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Invitrogen™ Cathelicidin Monoclonal Antibody (H7)
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Catalog No. PIMA518048
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100 μL
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PIMA518048 100 μL
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Catalog No. PIMA518048 Supplier Invitrogen™ Supplier No. MA518048
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Description

Mouse Monoclonal Antibody

This antibody is specific for human Cathelicidin (aa 115-121, NQARGSF). The immunogen was prepared using partially purified human neutrophil membrane proteins (heparin Ultrogellectin affinity purification fractions in octyl glucoside). This target has a predicted molecular weight of 19 kDa.

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cathelicidin
Applications Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone H7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene CAMP
Gene Accession No. P49913
Gene Alias 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
Gene Symbols CAMP
Host Species Mouse
Immunogen Partially purified human neutrophil membrane proteins (heparin Ultrogellectin affinity purification fractions in octyl glucoside).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 820
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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