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Invitrogen™ Cathelicidin Polyclonal Antibody
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Catalog No. PIPA5120383
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100 μL
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PIPA5120383 100 μL
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Catalog No. PIPA5120383 Supplier Invitrogen™ Supplier No. PA5120383
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Description

Rabbit Polyclonal Antibody

Positive test controls include: MCF7, A-549, PC-3, SP2/0, mouse testis, mouse spleen. The target is usually found in the following locations: Secreted. Immunogen sequence: NKRFALLGDF FRKSKEKIGK EFKRIVQRIK DFLRNLVPR.

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cathelicidin
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene CAMP
Gene Accession No. P49913
Gene Alias 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
Gene Symbols CAMP
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 132-170 of human CAMP (NP_004336.3).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 316010, 820
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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