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Invitrogen™ Cathelicidin Polyclonal Antibody
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Catalog No. PIPA5110987
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100 μL
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PIPA5110987 100 μL
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Catalog No. PIPA5110987 Supplier Invitrogen™ Supplier No. PA5110987
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RSSDANLYRL LDLDPRPTMD GDPDTPKPVS FTVKETVCPR TTQQSPEDCD FKKDGLVKRC MGTVTLNQAR GSFDISCDKD NKRFALLGDF FRKSKEKIGK EFKRIVQRIK DFLRNLVPR Highest antigen sequence indentity to the following orthologs: Rat - 55%, Mouse - 54%.

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cathelicidin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CAMP
Gene Accession No. P49913
Gene Alias 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
Gene Symbols CAMP
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human Cathelicidin. Recombinant protein control fragment (Product #RP-90388).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 820
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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