Invitrogen™ Cathepsin H/K/L/V Recombinant Rabbit Monoclonal Antibody (2Q10F10)

Catalog No.	Quantity
PIMA535614	100 μL

Catalog No. PIMA535614 Supplier Invitrogen™ Supplier No. MA535614

Description

Cathepsin H/K/L/V Recombinant Rabbit Monoclonal Antibody (ARC1276)

Cathepsin H/K/L/V Recombinant Monoclonal Antibody for Western Blot

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: Cathepsin H/K/L/V
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Recombinant Monoclonal
• Clone: 2Q10F10
• Concentration: 0.25 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: CTSH
• Gene Accession No.: O35186, O60911, P00786, P06797, P07154, P07711, P09668, P43235, P49935, P55097
• Gene Alias: ACC4; ACC-4; ACC5; ACC-5; AI323530; AL022844; aleurain; Cat H; Cat K; cathepsin B3; Cathepsin BA; cathepsin H; Cathepsin H heavy chain; Cathepsin H light chain; Cathepsin H mini chain; Cathepsin K; cathepsin L2; cathepsin L2, preproprotein; cathepsin O; cathepsin O1; cathepsin O2; Cathepsin U; cathepsin V; Cathepsin X; catK; CATL2; CPSB; CTS02; CTSH; Ctsk; CTSL2; CTSO; CTSO1; CTSO2; CTSU; CTSV; minisatellite 10q detected by probe MMS10; MMS10-Q; Ms10q; N-benzoylarginine-beta-naphthylamide hydrolase; PKND; Pro-cathepsin H; PYCD; UNQ268/PRO305
• Gene Symbols: CTSH, CTSK, CTSL, CTSV
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Cathepsin L/V/K/H (P07711).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 13036, 13038, 13039, 1512, 1513, 1514, 1515, 25425, 25697, 29175
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG