Invitrogen™ Cathepsin H/K/L/V Recombinant Rabbit Monoclonal Antibody (JM10-78)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA532602

Catalog No. PIMA532602

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: Cathepsin H/K/L/V
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O35186, O60911, P00786, P06797, P07154, P07711, P09668, P43235, P49935, P55097
• Gene Symbols: CTSH, CTSK, CTSL, CTSV
• Immunogen: Synthetic peptide within Human Cathepsin aa 92-138.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Clone: JM10-78
• Conjugate: Unconjugated
• Gene: CTSH
• Gene Alias: ACC4; ACC-4; ACC5; ACC-5; AI323530; AL022844; aleurain; Cat H; Cat K; cathepsin B3; Cathepsin BA; cathepsin H; Cathepsin H heavy chain; Cathepsin H light chain; Cathepsin H mini chain; Cathepsin K; cathepsin L2; cathepsin L2, preproprotein; cathepsin O; cathepsin O1; cathepsin O2; Cathepsin U; cathepsin V; Cathepsin X; catK; CATL2; CPSB; CTS02; CTSH; Ctsk; CTSL2; CTSO; CTSO1; CTSO2; CTSU; CTSV; minisatellite 10q detected by probe MMS10; MMS10-Q; Ms10q; N-benzoylarginine-beta-naphthylamide hydrolase; PKND; Pro-cathepsin H; PYCD; UNQ268/PRO305
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 13036, 13038, 13039, 1512, 1513, 1514, 1515, 25425, 25697, 29175
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid