Invitrogen™ Cathepsin K Monoclonal Antibody (C1), Invitrogen™

Catalog No.	Quantity
PIMA543914	20 μL
PIMA543913	100 μL

Catalog No. PIMA543914

Supplier: Invitrogen™ MA543914

Description

Mouse Monoclonal Antibody

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

Specifications

• Antigen: Cathepsin K
• Applications: Western Blot
• Classification: Monoclonal
• Clone: C1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene: CTSK
• Gene Accession No.: O35186, P43235, P43236, P55097, Q3ZKN1, Q5E968, Q9GLE3
• Gene Alias: AI323530; Cat K; cathepsin K; Cathepsin O; cathepsin O1; cathepsin O2; Cathepsin X; catK; CTS02; CTSK; CTSO; CTSO1; CTSO2; MGC23107; minisatellite 10q detected by probe MMS10; MMS10-Q; Ms10q; PKND; PYCD
• Gene Symbols: CTSK
• Host Species: Mouse
• Immunogen: Ala115-Met329 (Accession P43235), with N-terminal His Tag.
• Purification Method: Protein A/G
• Quantity: 20 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100009334, 100054991, 101108972, 13038, 1513, 29175, 397569, 513038, 608843
• Target Species: Human, Mouse, Rat, Canine, Rabbit, Bovine, Sheep, Pig, Horse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b κ

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov