Invitrogen™ Cathepsin K Polyclonal Antibody

Catalog No.	Quantity
FEPA5144672	100 μL

Catalog No. FEPA5144672 Supplier Invitrogen™ Supplier No. PA5144672

Description

Rabbit Polyclonal Antibody

Positive control: Jurkat cell lysate, K562 cell lysate, A549 cell lysate, U87MG cell lysate, A431 cell lysate. Predicted band size: 37 kDa Subcellular Location: Lysosome, Secreted, Apical cell membrane.

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

Specifications

• Antigen: Cathepsin K
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: CTSK
• Gene Accession No.: P43235
• Gene Alias: AI323530; Cat K; cathepsin K; Cathepsin O; cathepsin O1; cathepsin O2; Cathepsin X; catK; CTS02; CTSK; CTSO; CTSO1; CTSO2; MGC23107; minisatellite 10q detected by probe MMS10; MMS10-Q; Ms10q; PKND; PYCD
• Gene Symbols: CTSK
• Host Species: Rabbit
• Immunogen: Synthetic peptide within Human Cathepsin K aa 101-250/329.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1513
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG