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Invitrogen™ Cathepsin K Polyclonal Antibody
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Catalog No. PIPA514270
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400 μL
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PIPA514270 400 μL
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Catalog No. PIPA514270 Supplier Invitrogen™ Supplier No. PA514270
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Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, porcine, non-human primate and rabbit based on sequence homology.

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cathepsin K
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene CTSK
Gene Accession No. P43235, P55097
Gene Alias AI323530; Cat K; cathepsin K; Cathepsin O; cathepsin O1; cathepsin O2; Cathepsin X; catK; CTS02; CTSK; CTSO; CTSO1; CTSO2; MGC23107; minisatellite 10q detected by probe MMS10; MMS10-Q; Ms10q; PKND; PYCD
Gene Symbols CTSK
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 207-237 amino acids from the central region of human CTSK.
Purification Method Protein A, Antigen affinity chromatography
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13038, 1513
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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