Invitrogen™ Cathepsin K Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA514270

Catalog No. PIPA514270

Description

This antibody is predicted to react with bovine, porcine, non-human primate and rabbit based on sequence homology.

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

Specifications

• Antigen: Cathepsin K
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CTSK
• Gene Alias: AI323530; Cat K; cathepsin K; Cathepsin O; cathepsin O1; cathepsin O2; Cathepsin X; catK; CTS02; CTSK; CTSO; CTSO1; CTSO2; MGC23107; minisatellite 10q detected by probe MMS10; MMS10-Q; Ms10q; PKND; PYCD
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 13038, 1513
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P43235, P55097
• Gene Symbols: CTSK
• Immunogen: KLH conjugated synthetic peptide between 207-237 amino acids from the central region of human CTSK.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG