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Invitrogen™ Cathepsin O Polyclonal Antibody
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Catalog No. PIPA528285
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100 μL
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PIPA528285 100 μL
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Catalog No. PIPA528285 Supplier Invitrogen™ Supplier No. PA528285
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2, HCT116. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin O maintains the structural features characteristic of other cysteine proteinases including the active site cysteine residue that is involved in covalent intermediate formation during peptide hydrolysis. Cathepsin O is an endoproteinase that may be involved in extracellular matrix degradation. Cathepsin O is abundantly expressed in the ovary, kidney and placenta with lower levels found in thymus and skeletal muscle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cathepsin O
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene CTSO
Gene Accession No. P43234
Gene Alias A330105D01Rik; A430056C07; AI118514; cathepsin O; Ctso; CTSO1; LOC684529; similar to cathepsin O
Gene Symbols CTSO
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Cathepsin O. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1519
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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